abstract：INTRODUCTION:In vitro studies and ambulatory ECG recordings from the MERLIN TIMI-36 clinical trial suggest that the novel antianginal agent ranolazine may have the potential to suppress atrial arrhythmias. However, there are no reports of effects of ranolazine on atrial electrophysiologic properties in large intact ani...

journal_title：Journal of cardiovascular electrophysiology

authors： Kumar K,Nearing BD,Carvas M,Nascimento BC,Acar M,Belardinelli L,Verrier RL

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Myocardial depolarization can be altered by varying pacing stimulus output. This may have implications on response rates for cardiac resynchronization therapy (CRT). The purpose of our study was to determine the relationship of left ventricular (LV) pacing stimulus intensity to measures of depolarization and...

journal_title：Journal of cardiovascular electrophysiology

authors： Theis C,Bavikati VV,Langberg JJ,Lloyd MS

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The vein of Marshall (VOM), which exists along the left lateral isthmus (LLI), constitutes a muscular connection between the coronary sinus (CS) and the left atrium (LA). We hypothesized that anatomical variation of the VOM affects the bidirectional block of LLI and the clinical outcome in patients with nonp...

journal_title：Journal of cardiovascular electrophysiology

authors： Choi JI,Pak HN,Park JH,Choi EJ,Kim SK,Kwak JJ,Jang JK,Hwang C,Kim YH

更新日期：2009-06-01 00:00:00

abstract：:Catheter ablation for ventricular tachycardia (VT) is becoming an essential component of the successful management of patients with structural heart disease and refractory ventricular arrhythmias. Despite detailed mapping and ablation from the endocardium, nearly a third of VT circuits remain inaccessible. Pericardial...

journal_title：Journal of cardiovascular electrophysiology

authors： Tedrow U,Stevenson WG

更新日期：2009-06-01 00:00:00

abstract：INTRODUCTION:The purpose of this investigation is to evaluate whether a prolonged detection interval for life threatening ventricular tachyarrhythmia (VT) is able to reduce therapies (Rx) delivered by an implantable cardioverter/defibrillator (ICD). Until now, only the PREPARE trial demonstrated a reduction of ICD Rx i...

journal_title：Journal of cardiovascular electrophysiology

authors： Schwab JO,Gasparini M,Lunati M,Proclemer A,Kaup B,Santi E,Ligorio G,Klersy C,DE Sousa J,Okreglicki A,Arenal A,Wijffels M,Lemke B

更新日期：2009-06-01 00:00:00

abstract：:Macro-Reentrant ARVC epi-VT with a Focal Endo-Activation. A 55-year-old man with arrhythmogenic right ventricular cardiomyopathy underwent catheter ablation of ventricular tachycardia (VT) with left bundle branch block and left superior axis QRS morphology with an early precordial transition. Endocardial mapping durin...

journal_title：Journal of cardiovascular electrophysiology

authors： Yamada T,Plumb VJ,Tabereaux PB,Kay GN

更新日期：2009-06-01 00:00:00

abstract：INTRODUCTION:The optimal left ventricular (LV) pacing site for cardiac resynchronization therapy (CRT) is unclear. The current study aims to explore the clinical significance of LV lead concordance to delayed contraction segment in CRT. METHODS AND RESULTS:Concordant LV lead position was defined as the lead tip locate...

journal_title：Journal of cardiovascular electrophysiology

authors： Fung JW,Lam YY,Zhang Q,Yip GW,Chan WW,Chan GC,Chan JY,Yu CM

更新日期：2009-05-01 00:00:00

abstract：INTRODUCTION:We examined whether quantification of T-wave alternans (TWA) enhances this parameter's capacity to evaluate the risk for total and cardiovascular mortality and sudden cardiac death (SCD). METHODS AND RESULTS:The Finnish Cardiovascular Study (FINCAVAS) enrolled consecutive patients (n = 2,119; 1,342 men an...

journal_title：Journal of cardiovascular electrophysiology

authors： Minkkinen M,Kähönen M,Viik J,Nikus K,Lehtimäki T,Lehtinen R,Kööbi T,Turjanmaa V,Kaiser W,Verrier RL,Nieminen T

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVES:We sought to systematically investigate the role of the ligament of Marshall (LOM) and inferior left ganglionated plexi (ILGP) in modulating electrophysiological functions. METHODS:The following structures were exposed in 36 dogs: (1) LOM, (2) superior left GP (SLGP) near the junction of left superior pulmo...

journal_title：Journal of cardiovascular electrophysiology

authors： Lin J,Scherlag BJ,Niu G,Lu Z,Patterson E,Liu S,Lazzara R,Jackman WM,Po SS

更新日期：2009-03-01 00:00:00

abstract：INTRODUCTION:A low-energy (

journal_title：Journal of cardiovascular electrophysiology

authors： Lawo T,Deneke T,Schrader J,Danilovic D,Wenzel B,Buddensiek M,Muegge A

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:The presence of a single left superior vena cava in the absence of complex congenital heart disease is uncommon, and, in the absence of hemodynamic consequences, it would not be expected to result in cardiovascular signs or symptoms. Single case reports and our anecdotal experience suggested to us that this ...

journal_title：Journal of cardiovascular electrophysiology

authors： Ratnasamy C,Idriss SF,Carboni MP,Kanter RJ

更新日期：2009-02-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is the most frequent arrhythmia seen in clinical practice. Until recently, antiarrhythmic medications have been the only commonly employed treatment for maintaining sinus rhythm. However, antiarrhythmic medications have a modest long-term efficacy and the potential for serious side...

journal_title：Journal of cardiovascular electrophysiology

authors： Nair GM,Nery PB,Diwakaramenon S,Healey JS,Connolly SJ,Morillo CA

更新日期：2009-02-01 00:00:00

abstract：:The cavotricuspid isthmus (CVTI) is the well-established location of atrial tissue critical for the maintenance of typical atrial flutter. The CVTI begins at the electrically inert tricuspid valve and includes the atrial myocardium up to the inferior vena cava (IVC). In this article, we discuss relevant CVTI and right...

journal_title：Journal of cardiovascular electrophysiology

authors： Asirvatham SJ

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) and diabetes mellitus type 2 (DM2) often coexist; however, a small number of patients with DM2 undergoing catheter ablation (CA) of AF have been included in previous studies. The aim of this study was to evaluate safety and efficacy of ablation therapy in DM2 patients with drug ref...

journal_title：Journal of cardiovascular electrophysiology

authors： Forleo GB,Mantica M,De Luca L,Leo R,Santini L,Panigada S,De Sanctis V,Pappalardo A,Laurenzi F,Avella A,Casella M,Dello Russo A,Romeo F,Pelargonio G,Tondo C

更新日期：2009-01-01 00:00:00

abstract：:Calcium/calmodulin-dependent kinase II (CaMKII) is a multifunctional serine/threonine kinase widely distributed in a number of tissue types. Activation of CaMKII has been linked to important downstream physiological processes, including apoptosis, hypertrophy, and arrhythmia in the heart. Pharmacological or genetic in...

journal_title：Journal of cardiovascular electrophysiology

authors： Erickson JR,Anderson ME

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:Primary prevention ICD trials have excluded patients with CKD. Comorbidities and lower life expectancy in patients with CKD make the benefit of primary prevention ICD implantation uncertain. METHODS:A decision analysis model was devised to evaluate the risks and benefits of implantable cardioverter-defibr...

journal_title：Journal of cardiovascular electrophysiology

authors： Amin MS,Fox AD,Kalahasty G,Shepard RK,Wood MA,Ellenbogen KA

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:We conducted this study to examine the effect of the ICD on the outcomes of patients with prior coronary revascularization enrolled in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) and to assess the association of time from coronary revascularization to enrollment with death and sudden cardiac...

journal_title：Journal of cardiovascular electrophysiology

authors： Al-Khatib SM,Hellkamp AS,Lee KL,Anderson J,Poole JE,Mark DB,Bardy GH,scd-heft investigators.

更新日期：2008-10-01 00:00:00

abstract：INTRODUCTION:Repolarization dynamics, reflecting adaptation of QT to changing heart rate, is considered a marker of unfavorable prognosis in patients with heart diseases. We aimed to evaluate the prognostic value of QT/RR slope in predicting total mortality (TM) and sudden death (SD) in patients with congestive heart f...

journal_title：Journal of cardiovascular electrophysiology

authors： Cygankiewicz I,Zareba W,Vazquez R,Almendral J,Bayes-Genis A,Fiol M,Valdes M,Macaya C,Gonzalez-Juanatey JR,Cinca J,Bayes de Luna A,MUSIC Investigators.

更新日期：2008-10-01 00:00:00

abstract：:We report the case of a 71-year-old man with two atrial tachycardias evolving simultaneously and independently in two dissociated regions after extensive ablation for chronic atrial fibrillation. One tachycardia was a focal tachycardia originating from the right inferior pulmonary vein and activating the posterior lef...

journal_title：Journal of cardiovascular electrophysiology

authors： Matsuo S,Lim KT,Knecht S,Arantes L,Haïssaguerre M

更新日期：2008-09-01 00:00:00

abstract：:Atrial fibrillation (AF) is a progressive disease in which arrhythmia-induced remodeling facilitates evolution from paroxysmal AF to persistent and permanent AF. Changes in electrical, structural, and contractile properties of cardiac tissue that are thought to underlie AF maintenance and progression are reviewed. Als...

journal_title：Journal of cardiovascular electrophysiology

authors： Cohen M,Naccarelli GV

更新日期：2008-08-01 00:00:00

abstract：INTRODUCTION:While some posteroseptal and left posterior accessory pathways (APs) can be ablated on the tricuspid annulus or within the coronary venous system, others require a left-sided approach. "Fragmented" or double potentials are frequently recorded in the coronary sinus (CS), with a smaller, blunt component from...

journal_title：Journal of cardiovascular electrophysiology

authors： Pap R,Traykov VB,Makai A,Bencsik G,Forster T,Sághy L

更新日期：2008-07-01 00:00:00

abstract：INTRODUCTION:Cardiac resynchronization therapy (CRT) or biventricular pacing (BVP) is becoming an important treatment option in patients with severe congestive heart failure (CHF) and electrical dyssynchrony. When combined with implantable cardioverter-defibrillator (ICD) therapy, cardiac resynchronization therapy with...

journal_title：Journal of cardiovascular electrophysiology

authors： Nayak HM,Verdino RJ,Russo AM,Gerstenfeld EP,Hsia HH,Lin D,Dixit S,Cooper JM,Callans DJ,Marchlinski FE

更新日期：2008-07-01 00:00:00

abstract：INTRODUCTION:Complex fractionated atrial electrograms (CFAE) may identify critical sites for perpetuation of atrial fibrillation (AF) and provide useful targets for ablation. Current assessment of CFAE is subjective; automated detection algorithms may improve reproducibility, but their utility in guiding ablation has n...

journal_title：Journal of cardiovascular electrophysiology

authors： Porter M,Spear W,Akar JG,Helms R,Brysiewicz N,Santucci P,Wilber DJ

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The value of signal-averaged ECG (SAECG) in the risk stratification of Chagas disease (ChD), a potentially lethal illness prevalent in Latin America, remains controversial. The aim of this prospective longitudinal study was to determine the prognostic value of SAECG in ChD, using multivariate models with oth...

journal_title：Journal of cardiovascular electrophysiology

authors： Ribeiro AL,Cavalvanti PS,Lombardi F,Nunes Mdo C,Barros MV,Rocha MO

更新日期：2008-05-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) may occasionally affect athletes by impairing their ability to compete, and leading to noneligibility at prequalification screening. The impact of catheter ablation (CA) in restoring full competitive activity of athletes affected by AF is not known. The aim of our study was to inve...

journal_title：Journal of cardiovascular electrophysiology

authors： Furlanello F,Lupo P,Pittalis M,Foresti S,Vitali-Serdoz L,Francia P,De Ambroggi G,Ferrero P,Nardi S,Inama G,De Ambroggi L,Cappato R

更新日期：2008-05-01 00:00:00

abstract：:After pulmonary vein isolation for the treatment of atrial fibrillation, clinical arrhythmia recurrence is often a result of vein reconnection. By selectively visualizing scarred tissue, delayed enhancement magnetic resonance imaging may provide for a noninvasive means to identify gaps in radiofrequency ablation lines...

journal_title：Journal of cardiovascular electrophysiology

authors： Reddy VY,Schmidt EJ,Holmvang G,Fung M

更新日期：2008-04-01 00:00:00

abstract：INTRODUCTION:Brugada syndrome (BrS) is an inherited disorder that predisposes some subjects to sudden cardiac death (SCD). It is not well established which BrS patients are at risk of severe arrhythmias. Our aim was to study whether standard 12-lead electrocardiogram (ECG) would give useful information for this purpose...

journal_title：Journal of cardiovascular electrophysiology

authors： Junttila MJ,Brugada P,Hong K,Lizotte E,DE Zutter M,Sarkozy A,Brugada J,Benito B,Perkiomaki JS,Mäkikallio TH,Huikuri HV,Brugada R

更新日期：2008-04-01 00:00:00

abstract：INTRODUCTION:The incidence of left atrial appendage (LAA) thrombus in patients with paroxysmal atrial fibrillation (PAF) who present for pulmonary vein antrum isolation procedure (PVAI) is unknown. METHODS AND RESULTS:All consecutive patients from January 2000 to June 2004 who underwent a PVAI received a computed tomo...

journal_title：Journal of cardiovascular electrophysiology

authors： Khan MN,Usmani A,Noor S,Elayi S,Ching CK,Di Biase L,Patel D,Burkhardt JD,Cummings J,Schweikert R,Saliba W,Natale A

更新日期：2008-04-01 00:00:00

abstract：:Similar to the surgical mini-maze procedure, the posterior "box" lesion set employs linear ablation lesions along the anterior aspects of both sets of PVs connected by a roof line and an inferior line to electrically isolate the PVs and complete posterior LA wall en masse. However, creating fully transmural linear atr...

journal_title：Journal of cardiovascular electrophysiology

authors： Reddy VY,Neuzil P,D'Avila A,Ruskin JN

更新日期：2008-03-01 00:00:00

abstract：:Myasthenia gravis is an autoimmune disorder of the nervous system typically mediated by antibodies against the nicotinic acetylcholine receptor at the neuromuscular junction. Treatment of myasthenia gravis frequently involves the use of cholinesterase inhibitors such as pyridostigmine. Treatment with these agents has ...

journal_title：Journal of cardiovascular electrophysiology

authors： Gehi A,Benatar M,Langberg J

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:When double potentials (DP) on the line of block are difficult to see, we propose another simple method to verify complete bidirectional block (CBDB) at the end of an atrial flutter ablation. We measured the interval between the electrograms immediately on either side of the line of block on a multipole cath...

journal_title：Journal of cardiovascular electrophysiology

authors： Zambito PE,Palma EC

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Atrial fibrillation (AF) is the most commonly encountered clinical arrhythmia, predominantly affecting elderly patients. There is a continued need for new antiarrhythmic drugs to treat the ever-increasing number of patients with this arrhythmia. Dronedarone is a new antiarrhythmic compound currently being de...

journal_title：Journal of cardiovascular electrophysiology

authors： Hohnloser SH,Connolly SJ,Crijns HJ,Page RL,Seiz W,Torp-Petersen C

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Echocardiography is widely used to optimize CRT programming, but it is time-consuming. This study aimed to correlate the optimal interventricular pacing (V-V) interval obtained by echo with the optimal V-V interval obtained by a simpler method based on the surface ECG. METHODS AND RESULTS:Three V-V interv...

journal_title：Journal of cardiovascular electrophysiology

authors： Vidal B,Tamborero D,Mont L,Sitges M,Delgado V,Berruezo A,Díaz-Infante E,Tolosana JM,Paré C,Brugada J

更新日期：2007-12-01 00:00:00

abstract：:This article reviews current evidence of non-antiarrhythmic agents for the prevention and maintenance of sinus rhythm in patients with atrial fibrillation. These nontraditional agents include angiotensin converting enzyme inhibitors, angiotensin receptor blockers, antiinflammatory agents, calcium channel blockers, and...

journal_title：Journal of cardiovascular electrophysiology

authors： Lally JA,Gnall EM,Seltzer J,Kowey PR

更新日期：2007-11-01 00:00:00

abstract：INTRODUCTION:It has been speculated that pacemaker current (I(f)) in human atria could play a role in causing ectopic atrial automaticity. Ivabradine is a novel selective and specific I(f) inhibitor in the sinus node that reduces heart rate without any negative inotropic effect. The aim of the study was to explore poss...

journal_title：Journal of cardiovascular electrophysiology

authors： El Chemaly A,Magaud C,Patri S,Jayle C,Guinamard R,Bois P

更新日期：2007-11-01 00:00:00

abstract：INTRODUCTION:Quinidine has been evaluated in patients with a short QT-1 syndrome caused by an IKr gain-of-function mutation of HERG. Recently, in vitro data with disopyramide showed an even stronger effect on the N588K mutant current. The aim of the present study was to test the in vivo effects of disopyramide in patie...

journal_title：Journal of cardiovascular electrophysiology

authors： Schimpf R,Veltmann C,Giustetto C,Gaita F,Borggrefe M,Wolpert C

更新日期：2007-11-01 00:00:00

abstract：INTRODUCTION:Permanent right ventricular (RV) pacing leads have been traditionally implanted in the right ventricular apex (RVA). Nowadays, some deleterious effects of RVA pacing have been recognized. The aim of this study was to evaluate the effect of different sites of RV pacing in patients with permanent atrial fibr...

journal_title：Journal of cardiovascular electrophysiology

authors： Muto C,Ottaviano L,Canciello M,Carreras G,Calvanese R,Ascione L,Iengo R,Accadia M,Celentano E,Tuccillo B

更新日期：2007-09-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation and atrial flutter often coexist. The long-term occurrence of atrial fibrillation in patients presenting with atrial flutter alone is unknown. We report the long-term follow-up in patients who underwent cavotricuspid isthmus ablation for treatment of lone atrial flutter. METHODS AND RE...

journal_title：Journal of cardiovascular electrophysiology

authors： Ellis K,Wazni O,Marrouche N,Martin D,Gillinov M,McCarthy P,Saad EB,Bhargava M,Schweikert R,Saliba W,Bash D,Rossillo A,Erciyes D,Tchou P,Natale A

更新日期：2007-08-01 00:00:00

abstract：INTRODUCTION:Following conversion of atrial fibrillation (AF), QT interval transiently and variably prolongs and can trigger torsades de pointes (TdP). However, quantitative analysis of risk in this setting is difficult because cycle length variability during AF makes rate-corrected QT impossible to calculate. In this ...

journal_title：Journal of cardiovascular electrophysiology

authors： Darbar D,Hardin B,Harris P,Roden DM

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:The optimal recording technique of the electrogram voltage for detecting abnormal atrial tissue remains unclear. The aim of this study was to compare the impact of various recording techniques on the electrogram voltage after the delivery of ablation therapy in the human right atrium (RA). MATERIAL AND METH...

journal_title：Journal of cardiovascular electrophysiology

authors： Lin YJ,Tai CT,Lo LW,Udyavar AR,Chang SL,Wongcharoen W,Tuan TC,Hu YF,Chiang SJ,Chen YJ,Chen SA

更新日期：2007-06-01 00:00:00